Learning our way towards a sustainable agri-food system Three cases from Sweden: Stockholm Farmers market, Ramsjö Community Supported Agriculture and Järna Initiative for Local Production

This research is based on case studies of the Stockholm Farmers Market, Ramsjö Community Supported Agriculture, and Järna Initiative for Local Production. These cases are examples of alternative consumerproducer links in the Swedish agri-food system. An adapted SWOT analysis highlights key strengths, weaknesses, opportunities and constraints in each case from the multiple perspectives of producers, consumers, the organization, as well as the environment and society. Diagrams show where learning opportunities exist in the three systems, and how the structure of the consumer-producer link influences learning processes. Implication assessments consider how each link may affect surrounding ecosystems and social aspects of the agri-food system. A framework for assessing a process of development identifies six components that contribute to agri-food system development. Four key issues are discussed in terms of their potential to significantly affect the development of the agri-food system: the length of the food chain linking producers and consumers, the definition of “local”, learning in the system, and what is really being sold – is it food, or values? Critical research questions are highlighted and recommended for future research

Anti-Nogo-A Immunotherapy Does Not Alter Hippocampal Neurogenesis after Stroke in Adult Rats

Ischemic stroke is a leading cause of adult disability, including cognitive impairment. Our laboratory has previously shown that treatment with function-blocking antibodies against the neurite growth inhibitory protein Nogo-A promotes functional recovery after stroke in adult and aged rats, including enhancing spatial memory performance, for which the hippocampus is critically important. Since spatial memory has been linked to hippocampal neurogenesis, we investigated whether anti-Nogo-A treatment increases hippocampal neurogenesis after stroke. Adult rats were subject to permanent middle cerebral artery occlusion followed 1 week later by 2 weeks of antibody treatment. Cellular proliferation in the dentate gyrus was quantified at the end of treatment, and the number of newborn neurons was determined at 8 weeks post-stroke. Treatment with both anti-Nogo-A and control antibodies stimulated the accumulation of new microglia/macrophages in the dentate granule cell layer, but neither treatment increased cellular proliferation or the number of newborn neurons above stroke-only levels. These results suggest that anti-Nogo-A immunotherapy does not increase post-stroke hippocampal neurogenesis

Large expert-curated database for benchmarking document similarity detection in biomedical literature search

Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe

An investigation of highbush blueberry floral biology and reproductive success in British Columbia

Vaccinium corymbosum (highbush blueberry) is and economically important crop in British Columbia and suffers from inconsistent and often inadequate pollination by the managed pollinator, the honeybee. The outcrossing strategy of blueberry requires a pollen vector; however honeybees are inefficient and choosey. One goal of this research was to investigate the variable attractiveness of blueberry flowers to pollinators, specifically focusing on odour, and the possibilities for improved pollination. Highbush blueberry flowers emit a wide range of volatile compounds that show heritability in the broad-sense. However, determining which compounds are important to pollinators is a challenging task and remains poorly understood. Pollinator choice was examined through monitoring of pollinators as well as determination of pollen movement through paternity analysis. There was no agreement between the analyses, which show that the genotypes Duke and Reka appear to attract more pollinators but the most common fathers are Bluecrop and Elliott. A second goal of this research was to examine reproductive success; and the discrepancy between attraction and reproduction could be due in part to the range in fertility observed among highbush blueberry genotypes. Inbreeding depression due to the use of a narrow breeding pool to develop genotypes is a potential cause of the observed range in fertility and offspring vigour. The degree to which inbreeding will increase homozygosity depends on the inheritance pattern of the tetraploid highbush blueberry; however, the current levels of inbreeding limit an accurate description of the inheritance pattern.Forestry, Faculty ofGraduat

Ultrasonication-Assisted Solvent Extraction of Quercetin Glycosides from ‘Idared’ Apple Peels

Quercetin and quercetin glycosides are physiologically active flavonol molecules that have been attributed numerous health benefits. Recovery of such molecules from plant matrices depends on a variety of factors including polarity of the extraction solvent. Among the solvents of a wide range of dielectric constants, methanol recovered the most quercetin and its glycosides from dehydrated ‘Idared’ apple peels. When ultra-sonication was employed to facilitate the extraction, exposure of 15 min of ultrasound wavelengths of dehydrated apple peel powder in 80% to 100% (v/v) methanol in 1:50 (w:v) solid to solvent ratio provided the optimum extraction conditions for quercetin and its glycosides. Acidification of extraction solvent with 0.1% (v/v) or higher concentrations of HCl led to hydrolysis of naturally occurring quercetin glycosides into the aglycone as an extraction artifact

Unmet Psychosocial Needs of Health Care Professionals in Europe During the COVID-19 Pandemic: Mixed Methods Approach

BackgroundThe COVID-19 pandemic severely affected everyday life and working conditions for most Europeans, particularly health care professionals (HCPs). Over the past 3 years, various policies have been implemented in various European countries. Studies have reported on the worsening of mental health, work-related stress, and helpful coping strategies. However, having a closer look is still necessary to gain more information on the psychosocial stressors and unmet needs of HCPs as well as nonmedical staff. ObjectiveThis study aimed to obtain quantitative information on job-related stressors of physicians and nurses and the coping strategies of HCPs and nonmedical staff at 2 periods of the COVID-19 pandemic. By further analyzing qualitative comments, we wanted to gain more information on the psychosocial stressors and unmet needs of HCPs as well as nonmedical staff on different levels of experience. MethodsA cross-sectional survey was conducted at 2 time points during the COVID-19 pandemic in several European countries. The first study period (T1) lasted between April 1 and June 20, 2020, and the second study period (T2) lasted between November 25, 2021, and February 28, 2022. On a quantitative level, we used a questionnaire on stressors for physicians and nurses and a questionnaire on coping strategies for HCPs and nonmedical staff. Quantitative data were descriptively analyzed for mean values and differences in stressors and coping strategies. Qualitative data of free-text boxes of HCPs and nonmedical staff were analyzed via thematic analysis to explore the experiences of the individuals. ResultsT1 comprised 609 participants, and T2 comprised 1398 participants. Overall, 296 participants made 438 qualitative comments. The uncertainty about when the pandemic would be controlled (T1: mean 2.28, SD 0.85; T2: mean 2.08, SD 0.90) and the fear of infecting the family (T1: mean 2.26, SD 0.98; T2: mean 2.02, SD 1.02) were the most severe stressors identified by physicians and nurses in both periods. Overall, the use of protective measures (T1: mean 2.66, SD 0.60; T2: mean 2.66, SD 0.60) and acquiring information about COVID-19 (T1: mean 2.29, SD 0.82; T2: mean 1.99, SD 0.89) were identified as the most common coping strategies for the entire study population. Using thematic analysis, we identified 8 themes of personal experiences on the micro, meso, and macro levels. Measures, working conditions, feelings and emotions, and social climate were frequently mentioned topics of the participants. In T1, feelings of isolation and uncertainty were prominent. In T2, feelings of exhaustion were expressed and vaccination was frequently discussed. Moreover, unmet psychosocial needs were identified. ConclusionsThere is a need for improvement in pandemic preparedness. Targeted vocational education measures and setting up of web-based mental health support could be useful to bridge gaps in psychosocial support needs in future crises

Cultural dimensions of workfare and welfare

I compare the treatment of two marginal recipient groups, not commonly regarded as “on welfare,” to that experienced by conventional welfare recipients and argue that we need an understanding of welfare that takes culture more seriously. Public discourse concerning welfare would be more enlightening if we could move beyond hegemonic concepts such as “economic self-sufficiency.” I propose thinking of welfare as a public subsidy for groups whose way of life is incompatible with economic self-sufficiency – an approach that enables us to consider culture explicitly in debates regarding the core populations affected by social policy